E-ISSN: 2774-2504 P-ISSN: 2775-0108 Open Access (CC BY-SA 4.0)
Artikel
Open Access (CC BY-SA 4.0) Peer Reviewed

PENGUJIAN AKTIVITAS ANTIMIKROBA EKSTRAK ETIL ASETAT DAN METANOL KAYU RANTING SENGON (Falcataria moluccana) SAKIT

Popy Listiani (Jurusan Analis Kesehatan, Institut Kesehatan Rajawali, Jawa Barat, Indonesia)
Popy Hasanah (Jurusan Analis Kesehatan, Institut Kesehatan Rajawali, Jawa Barat, Indonesia)
Alfi Rumidatul (Sekolah Ilmu dan Teknologi Hayati, Institut Teknologi Bandung, Jawa Barat, Indonesia)
Feldha Fadhila (Jurusan Analis Kesehatan, Institut Kesehatan Rajawali, Jawa Barat, Indonesia)
Yayan Maryana (Jurusan Farmasi, Politeknik Meta Industri, Jawa Barat, Indonesia)
Article Publication History
Received 16 Oct 2020
Revised 02 Apr 2021
Accepted 02 Apr 2021
Published Online 03 Apr 2021
10.53699/joimedlabs.v2i1.23
1.043
1.344
Scholar Citations
55-67

Abstract

Klebsiella pneumoniae, Shigella dysenteriae, Salmonella typhi, Escherichia coli, and Candida albicans are the microorganisms that most often infect. Infectious diseases can be cured and the transmission is minimized using various kinds of antibiotics.The search for antimicrobial compounds from nature is expected to reduce the negative effect of antibiotics. One of the plants suspected of having antimicrobial content is the sengon tree. This study aims to determine the ability of sengon sore wood extract with ethyl acetate and methanol as an antimicrobial solvent. The test method used is Kirby bauer with treatments 9%, 9.5%, 10%, 10.5%, and 11%. The result of this study showed that the ethyl acetate extract of sengon sick wood showed antimicrobial activity against Shigella dysenteriae at all concentrations and in Klebsiella pneumoniae only at a concentration of 11%, there’s no antimicrobial activity against E. coli. A Methanol extract of sengon sick twig wood showed antimicrobial activity against Klebsiella pneumoniae at concentrations of 10%, 10.5%, 11%, and on Candida albicans at all concentrations, but didn’t show antimicrobial activity against E. coli, S. typhi, and S. dysenteriae. Can be concluded that the ethyl acetate extract of sengon sick wood branches could inhibit the growth of Shigella dysenteriae and Klebsiella pneumoniae. Meanwhile, methanol extract of sengon sick twig wood can inhibit the growth of Klebsiella pneumoniae and Candida albicans.