Antibacterial activity of coriander seeds extract (Coriandrum sativum) against the growth of Streptococcus mutans

Main Article Content

Liah Kodariah
Eka Yuliani Amaliah
Tyas Ismi Fadhillah

Abstract

Background: Streptococcus mutans is the main cause of dental caries, previously known as part of the normal flora in the oral cavity which plays a role in the process of fermenting carbohydrates to produce acid, and causes tooth demineralization. Chemical-based medicinal products such as toothpaste and mouthwash. Continuous use of chemicals can cause side effects for users such as hypersensitivity, therefore an alternative treatment from natural ingredients such as coriander seeds which can inhibit bacterial growth is needed. Objective: This research aims to determine the lowest concentration of coriander seed extract in 0,75%, 1.5%, 3% inhibiting the growth of Streptococcus mutans. Methods: This study was conducted by soaking the test discs in coriander seed extract concentrations of 0.75%, 1.5% and 3%. each disc was inserted into the bacterial culture to be cultured, incubated and seen whether there was a clear zone or not. Result: Test results showed a clear zone at a concentration 1.5% with an average diameter of 1.5 mm, at concentration of 3% an average diameter of 3.7 mm and at concentration of 0.75% did not show clear zone. Conclusion: Based on the results of the study, the lowest concentration of coriander seed extract was obtained which was able to inhibit the growth of Streptococcus mutans bacteria, is at concentration of 1.5%, the diameter of the inhibition zone of coriander seed extract had weak antibacterial activity.

Article Details

How to Cite
Kodariah, L., Amaliah, E. Y., & Fadhillah, T. I. (2024). Antibacterial activity of coriander seeds extract (Coriandrum sativum) against the growth of Streptococcus mutans. Journal of Indonesian Medical Laboratory and Science (JoIMedLabS), 5(2), 96-104. https://doi.org/10.53699/joimedlabs.v5i2.149
Section
Artikel
Author Biography

Eka Yuliani Amaliah, Department of Medical Laboratory Technology, Faculty of Health, Institut Kesehatan Rajawali, Bandung, Indonesia

Department of Medical Laboratory Technology, Faculty of Health, Institut Kesehatan Rajawali, Bandung, Indonesia

References

Abranches, J., Zeng, L., Kajfasz, J. K., Palmer, S. R., Chakraborty, B., Wen, Z. T., Richards, V. P., Brady, L. J., & Lemos, J. A. (2018). Biology of Oral Streptococci. Microbiology Spectrum, 6(5), 1–18. https://doi.org/10.1128/microbiolspec.gpp3-0042-2018

Albar, F., & Wibawa, A. S. (2017). Pengaruh Perbandingan Cmc-Na Sebagai Gelling Agent Pada Sediaan Gel Ekstrak Bawang Daun ( Allium fistulosum L .) Terhadap Bakteri Staphylococcus Aureus The Effect Of Cmc-Na Comparison As Gelling Agent In Spring Onion ( Allium fistulosum L .) Extract Again. Jurnal Ilmiah Farmasi, 1–9.

mayanja, A., & Naranjo, J. (2014). Uji Aktivitas Antibakteri Ekstrak Etanol Daun Sirsak (Annona muricata L.) Terhadap Shigella flexneri Secara In Vitro. Applied Microbiology and Biotechnology, 85(1), 2071–2079.

Anggraeni, T., Ridwan, A., Kodariah Kelompok Keilmuan Fisiologi, L., & Hewan dan Sains Biomedika Sekolah Ilmu dan Teknologi Hayati, P. (2016). Ekstrak Etanol Seledri (Apium graveolens) Sebagai Anti-Atherogenik Pada Tikus (Rattus norvegicus) Yang Diinduksi Hiperlipidemia. Prosiding Symbion (Symposium on Biology Education), Prodi Pendidikan Biologi, FKIP, Universitas Ahmad Dahlan, Ldl, 171–188.

Bahar, A. (2015). Paradigma baru pencegahan karies gigi dalam menunjang kemajuan ilmu kedokteran gigi pencegahan. UI-Press. https://lib.ui.ac.id

Eliana, S., Nur, A., & Rini Maya Puspita. (2017). Pengaruh Ekstrak Biji Ketumbar (Coriandrum Sativum) Fraksi Etil Asetat Terhadap Pembentukan Massa Biofilm Bakteri Streptococcus mutans (Kajian In Vitro). https://etd.repository.ugm.ac.id/penelitian/detail/116306

Kemenkes RI. (2018). Hasil Riset Kesehatan Dasar Tahun 2018. Kementrian Kesehatan RI, 53(9), 1689–1699.

Kodariah, L., Ghasani, F., & Murtafi’ah, N. (2022). Antibacterial effect of corarian seed (Coriandrum sativum L.) extract on Streptococcus mutans. Asian Journal of Health and Applied Sciences, 1(1), 7–14. https://doi.org/10.53402/ajhas.v1i1.7

Listyorini, D. (2019). Uji Daya Hambat Antibakteri Kombinasi Ekstrak Daun Sirih Merah (Piper crocatum) dan Daun Kelor ( Moringa oleifera L.) Terhadap Bakteri Eschericia coli. Karya Tulis Ilmia Stikes Bhakti Husada Mulia Madiun.

Magani, A. K., Tallei, T. E., & Kolondam, B. J. (2020). Uji Antibakteri Nanopartikel Kitosan terhadap Pertumbuhan Bakteri Staphylococcus aureus dan Escherichia coli. Jurnal Bios Logos, 10(1), 7. https://doi.org/10.35799/jbl.10.1.2020.27978

Majid, N. (Nikmah), Majid, A. (Abdul), & Paulus, A. Y. (Aysanti). (2022). Identifikasi Golongan Senyawa Tanin, Flafonoid, Alkoloid dan Saponin sebagai Senyawa Antibakteri pada Ekstrak Daun Kelor (Moringa Oleifera L.) Asal Kota Kupang. CHMK Applied Scientific Journal, 5(1), 1–7. https://doi.org/10.37792/CASJ.V5I1.1133

Marinho, V. T., dos Reis, A. C., & da Costa Valente, M. L. (2022). Efficacy of Antimicrobial Agents in Dentifrices: A Systematic Review. Antibiotics, 11(10). https://doi.org/10.3390/antibiotics11101413

Mutiasari, A. S. (2019). Uji Aktivitas Antibakteri Minyak Atsiri Biji Ketumbar (Coriandrum Sativum L.) dan Nanoemulsinya terhadap Staphylococcus epidermidis. https://repository.unej.ac.id/xmLui/handle/123456789/90980

Nasrudin, wahyono, Mustofa, R. A. (2017). Isolasi Senyawa Steroid Dari Kukit Akar Senggugu ( Clerodendrum serratum L.Moon ). Pharmacon?:Journal Ilmiah Farmasi - Unsrat, 6(3).

Nikmah, Majid, A., & Paulus, A. Y. (2022). Identifikasi Golongan Senyawa Tanin, Flavonoid, Alkaloid dan Saponin Sebagai Senyawa Antibakteri Pada Ekstrak Daun Kelor (Moringa oleifera L.) Asal Kota Kupang. CHM-K Applied Scientific Journal, 5(1), 1–7.

Pakaya, M. S., Akuba, J., Papeo, D. R. P., Makkulawu, A., & Puspitadewi, A. A. (2022). Isolasi dan karakterisasi bakteri endofit dari akar pare (Momordica charantia L). Journal Syifa Sciences and Clinical Research, 4(1), 301–309.

Pawar, V. A., Bhagat, T. B., Toshniwal, M. R., Mokashi, N. D., & Khandelwal, K. R. (2014). Formulation and Evaluation of Dental Gel Containing Essential Oil of Coriander Against Oral Pathogens. International Research Journal of Pharmacy, 4(10), 48–54. https://doi.org/10.7897/2230-8407.041012

Su’aidi, M. N. (2019). Isolasi dan Identifikasi Bakteri Resisten Selenate (SeO4 2-) dari Sedimen Mangrove Pantai Banyuglugur Kabupaten Situbondo, Jawa Timur.

Sukma, D. R., Berawi, K. N., & Wahyudo, R. (2018). Pengaruh Pemberian Bawang Putih (Allium Sativum) terhadap Penyakit Dislipidemia. Jurnal Medula, 8(1), 49–53. https://juke.kedokteran.unila.ac.id/index.php/medula/article/view/2099

Widiani, P. I., & Pinatih, K. J. P. (2020). Uji Daya Hambat Ekstrak Etanol Daun Kelor (Moringa oleifera) Terhadap Pertumbuhan Bakteri Methicillin Resistant Staphylococcus aureus (MRSA). Medika Udayana, 9(3), 22–28. https://ojs.unud.ac.id/index.php/eum

Yeni Meryandini, A., & Sunarti, T. C. (2016). Penggunaan Substrat Whey Tahu Untuk Produksi Biomassa Oleh Pediococcus pentosaceus E.1222. Jurnal Teknologi Industri Pertanian, 26(3), 284–293.